​Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after traumatic brain injury (TBI), reverse cognitive impairments in Down Syndrome, prevent noise-related hearing loss, fight certain types of prostate cancer, and even enhance cognition in healthy animals.
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In the new study, published Dec. 1, 2020, in the open-access journal eLife, researchers showed rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.

“Two-thirds of adults throughout all developed nations fail to obtain the recommended eight hours of nightly sleep.
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“I doubt you are surprised by this fact, but you may be surprised by the consequences. Routinely sleeping less than six or seven hours a night demolishes your immune system, more than doubling your risk of cancer. Insufficient sleep is a key lifestyle factor determining whether or not you will develop Alzheimer’s disease. Inadequate sleep—even moderate reductions for just one week—disrupts blood sugar levels so profoundly that you would be classified as pre-diabetic. Short sleeping increases the likelihood of your coronary arteries becoming blocked and brittle, setting you on a path toward cardiovascular disease, stroke, and congestive heart failure. Fitting Charlotte Brontë’s prophetic wisdom that ‘a ruffled mind makes a restless pillow,’ sleep disruption further contributes to all major psychiatric conditions, including depression, anxiety and suicidality.”

Id like to think moderate republicans could act as such too, but at least in my social circle, they all changed their party affiliations because of Trump.

​As far as politics goes, both sides are moving further apart, which is a bad sign. but it would seem the left has moved a bit further away from the center than the right. The chart below is from Pew.

After all, in LA, illegal immigrants (err, undocumented workers) have been elected to public office while members of congress and the Senate have called to abolish ICE which is at least as over-the-top as the "muslim ban" (which as implemented was a terrible law, but not a muslim ban).

But coming back to this, I don't think a conservative mayor in a conservative city would have ever let a fascist or neo-confederate "South is rising again" autonomous zone in their city for a day. Seattle's mayor let it go on for well over a month.

As far as politics goes, both sides are moving further apart, which is a bad sign. but it would seem the left has moved a bit further away from the center than the right. The chart below is from Pew.

After all, in LA, illegal immigrants (err, undocumented workers) have been elected to public office while members of congress and the Senate have called to abolish ICE which is at least as over-the-top as the "muslim ban" (which as implemented was a terrible law, but not a muslim ban).
​
But coming back to this, I don't think a conservative mayor in a conservative city would have ever let a fascist or neo-confederate "South is rising again" autonomous zone in their city for a day. Seattle's mayor let it go on for well over a month.

cool graph.

Let me explain to you the reality though.

The nation has moved much further to the right the last 40 years. Things like the New Deal, Great Society, Medicare, Medicaid, Voting Rights Act, etc, all these things are looked down upon. The Right is trying their best to systematically take away voting rights, take away women's right, normalize right wing fanaticism.

Now "undocumented" worker has been elected to a public office. The one person I've heard about was APPOINTED to a BOARD that relates to immigration. She's an attorney! She was brought here by her parents when she was like 12 years old. What's your expectation? Why is this an issue?

As for the Conservative Mayor argument, you must be kidding. Have you lived in the south? They don't need a zone: IT'S THE STATE.

You think shooting a dude and "standing your ground" is moving left? Do you use unions with any power? Do you see union membership on the rise? Do you see environmentalists really getting their way (that it's even a left issue is super fucking embarrassing)? Do you see corporations LOSING POWER? Or do you see a corporation being given the rights of a man?
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Not sure what you're looking at, but the world has MOVED RIGHT because of the courts and the deference to corporations. Liberals are fighting for human rights, and it's not because they've gained them. Conservatives are fighting for making sure someone with less than them doesn't get more.

Woah bud, thanks for explaining reality to me.

Anyways, the idea that conservatism is just being a prostitute to corporations is, well, kind of a caricature. Indeed, both parties seem to be prostitutes to corps (with Republicans being especially whorish to oil, Dems especially whorish to Silicon Valley and both exceptionally whorish to Wall Street). Both bases tend to be anti-Wall Street. And the populist right is definitely anti-Wall Street. So what does it mean to be moving toward the right if that "right" is populist?

And all the South is a "conservative autonomous zone " (including Georgia and Virginia, which went for Biden). Uh huh... But California, Oregon and Washington are just moderate, right?

I would say things are moving in three directions simultaneously; 1) more establishment power, 2) increased local partisanship, 3) cultural leftward shift. There is no general shift to the right.

As far as establishment power; this is obvious. NSA and CIA spying run amok, endless wars, massive consolidation of wealth in Silicon Valley/Wall Street, etc. I've seen opposition to this across the spectrum and Trump even broke the mold by harshly criticizing some of this ('Iraq war was the worst mistake in US history" etc.) Populism itself is generally anti-corporate after all. (Although I think Trump just used populist rhetoric and governed like Bush.)

Major entitlement programs are not under threat (other than solvency). The Republicans want to get rid of Obamacare, not Medicare. That's the reactionary idea of going back to 2009. Bush's attempt to partially privatize social security went nowhere and was pretty much dropped. As far as attacks on voting rights, I don't know. There seems to be so much bullshit here with gerrymandering and lawfare nonsense. I will say that ballot harvesting is ripe for abuse. It also didn't seem like anyone had any trouble voting in 2020.

- But just go down the issues:
- Gay Marriage: Legal and Republicans have pretty much accepted it (under Trump no less)
- Transgenderism: Not even on the table 10 years ago, now we're "transitioning" 7 year olds.
- Immigration: Record levels, mainstream won't even call illegal immigration "illegal immigration" anymore. Trump made a few cuts around the edges but Biden will undo those.
- Diversity Stuff: All sorts of government, corporate and university initiatives
- Eduction: Pretty much dominated by woke, postmodernist nonsense
- Marketing: Woke capitalism is about as annoying and shallow as it gets.
- Environmentalism: Lots of subsidies to green tech and grants but only mild progress on legislation. That being said, the main stuff people care about (clean rivers, air, etc.) was mostly taken care of decades ago. The issues now are more abstract and "out there in the distance" i.e. global warming and soil depletion
- Christianity: Fading in importance both politically and civically
- Drugs: Many states have legalized marijuana, the Congress voted to legalize it and Oregon decriminalized drugs.
- Criminal Justice Reform: The bipartisan agreement to get hard on crime (which most black leaders also approved of by the way. Now there's actually bipartisan agreement we have to go the other way and Trump actually took steps in that direction
- Government spending: About what it was in 1950 as a % of GDP
- Federal Taxes: The top tax bracket is about what it was in mid-80s
- The Deficit: A Bipartisan trainwreck (although I blame the Republicans more)

It's true that unions are down and inequality up. And part of that is the pro "business" Republicans. Much of that was driven by globalization, which was a bipartisan consensus. And much by technology's ability to consolidate wealth, which just hasn't been addressed. But another part of it is because the Democrats seemed to give up on the working class and focus exclusively on wokeness and hating Russia.

The rest is red and blue states moving further apart. So gun laws get stricter in blue states and looser in red. Abortion laws get stricter in blue states and looser in red [backwards, sorry], etc. This is more a sign of the increasing partisan divide in the country that I don't see getting better anytime soon.
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Sorry for the length. This post really got away from me.

Holy shiz, I have to stop you right from the jump!

Gay Marriage? Why is that a "liberal" concept?

Transgenderism? Same question.
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Diversity "Stuff"? AGAIN, Why is this LIBERAL?

"Eduction" - love that you spelled that wrong, so I'll let it sit.

Christianity - Republicans don't even care about it. They voted for Trump. They don't care about Jesus - they care about cults. No one is stopping anyone from being a Christian. Sorry it doesn't dominate our life, like in the classrooms, or in the LABS or in the HOSPITALS. Bush made it so you can consider Christianity with "Faith based initiatives." There's practically a Christianity test to a congress person in 40+ American States.

Drugs - Sure, that's liberal. Thank goodness. But Republicans only supported drug reform when White kids started using oxycontin, etc. They never gave any fucks when it wasn't their kids, or the kid from the church. This gets back to them only really give fucks about their thing, which was an original point. This is also the "criminal justice" thing. So, yeah, this isn't a Democrat/Liberal wind. It's Republicans getting on board because it helps their constituents now. You must not remain Crack cocaine vs cocaine.

Government spending? See WARS. See deficits under all presidents. Tell me what you come up with. Yes, you got it right, Republicans. Liberal programs are designed to help. What are Republican programs for? Wait, what are their programs?

Yes, red and blue further apart. Red pretending they can't own machine guns and show up at Governor's mansion. Blue upset innocent people get killed and rightwing groups raise funds to help that person, aka, The George Zimmerman Effect.

Love ya.

Good God David this is such shill partisan hackery it's embarrassing. I think I'm gonna go ahead and disengage before wasting anymore going around in circles on this.

Sorry to tell you, but the things you're claiming are "liberal" ideas are quite often just human rights.
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Check the most recent SCOTUS decision on religion. Y'all be fine.

Sorry to tell you, but conservative ideas are quite often just muh freedom and loving 'Merica.​

SpaceX and Tesla  CEO Elon Musk said Tuesday that he has moved to Texas, confirming months of speculation that the billionaire would leave California, a state of which he has become increasingly critical. Musk confirmed the move during an interview at the The Wall Street Journal’s CEO Council annual summit.

His remarks confirmed a CNBC report that Musk had told friends of his intent to move to Texas.
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The move coincides with a number of SpaceX and Tesla-related projects in Texas, the sale of several of Musk’s Los Angeles homes as well as his disagreement with how California public officials have handled the COVID-19 pandemic.

In the last decade, about 90% of U.S. population growth has been in suburbs and exurbs, with CBDs accounting for .8% of growth and the entire urban corps for roughly 10%. In this span, population growth of some of the most alluring core cities — New York, Chicago, Philadelphia — has declined considerably. Manhattan and Brooklyn, have both seen their rate of growth decline by more than 85% since 2011. Nationally, core counties lost over 300,000 net domestic migrants In 2016 (with immigrants replacing some some of those departees), while their suburbs gained nearly 250,000.

Dense urban living has been linked to many new diseases (including psychosis, cancer, and cardiovascular disease) over the past decade, and new research contradicts the old narrative some architectural and urbanists are still spreading about the supposed healthiness of city living. Research shows that proximity and exposure to parks and outside spaces is linked to better health outcomes and life expectancy — and that the best place for most people to have this is in suburbia, given how difficult and expensive it would be to dramatically expand park spaces in densely populated cities.